If you want to move a large or long unit, such as an entire production line or skyline, and you use "E" to move it, your cursor will automatically center.

I would prefer it without auto-centering, but with the cursor anchored where I grab the unit (for example, at the bottom left corner or at one end of the skyline).

Currently, I'm juggling all over the island just to move the unit one grit up or to the right. :-)